Two Novel Asymmetric Eremophilane Dimers from the Roots of Ligularia virgaurea

Two Novel Asymmetric Eremophilane Dimers from the Roots of Ligularia virgaurea

Virgaurol A (1) and B (2), two novel dimeric eremophilanes in whose structures the two asymmetric sesquiterpene units are connected by a C–C bond directly, have been isolated from the roots of Ligularia virgaurea. Their structures were determined by comprehensive spectral analysis. Compound 1 was ev...

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Veröffentlicht in:Chemistry letters 2008-03, Vol.37 (3), p.346-347
Hauptverfasser: Zhang, Zhan-Xin, Wang, Chun-Ming, Fei, Dong-Qing, Jia, Zhong-Jian
Format: Artikel
Sprache:eng
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Zusammenfassung:Virgaurol A (1) and B (2), two novel dimeric eremophilanes in whose structures the two asymmetric sesquiterpene units are connected by a C–C bond directly, have been isolated from the roots of Ligularia virgaurea. Their structures were determined by comprehensive spectral analysis. Compound 1 was evaluated for its in vitro cytotoxic activity against human leukemia (HL-60), human hepatoma (SMMC-7721), and human cervical carcinoma (HeLa) cells.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2008.346