Highly Efficient Methanolysis of Bicyclic β-Lactams to β-Amino Ester Using Silica Chloride
Silica chloride is used as an effective heterogeneous catalyst for the methanolysis of highly constrained cyclic β-lactam to afford β-amino ester under mild acidic conditions with quantitative yields.
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| Veröffentlicht in: | Chemistry letters 2006-09, Vol.35 (9), p.1004-1005 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Silica chloride is used as an effective heterogeneous catalyst for the methanolysis of highly constrained cyclic β-lactam to afford β-amino ester under mild acidic conditions with quantitative yields. |
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| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.2006.1004 |