Increased von Willebrand factor in migraine

The authors determined von Willebrand factor (vWF) in 63 persons with migraine, 11 persons with migraine and prior stroke, and 35 frequency-matched controls. Additional studies were done in a subset with migraine without aura who were headache free for >7 days. Migraineurs with prior stroke had s...

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Veröffentlicht in:	Neurology 2001-07, Vol.57 (2), p.334-336
Hauptverfasser:	TIETJEN, G. E, AL-QASMI, M. M, ATHANAS, K, DAFER, R. M, KHUDER, S. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Female Humans Male Medical sciences Middle Aged Migraine Disorders - blood Migraine Disorders - complications Neurology Risk Factors Stroke - blood Stroke - complications Vascular diseases and vascular malformations of the nervous system von Willebrand Factor - metabolism
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Zusammenfassung:	The authors determined von Willebrand factor (vWF) in 63 persons with migraine, 11 persons with migraine and prior stroke, and 35 frequency-matched controls. Additional studies were done in a subset with migraine without aura who were headache free for >7 days. Migraineurs with prior stroke had significantly higher vWF antigen (170% versus 106%) and activity (162% versus 108%) than the control group. vWF antigen (126%) and activity (130%) were also significantly higher in migraineurs without stroke. Multimers and protease activity were normal in the interictal subset.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/WNL.57.2.334