261 The Epidemiology of Diabetes in Pregnancy and Maternal Characteristics in Northern Greece

Aims: To determine the prevalence of diabetes in pregnancy and evaluate maternal characteristics according to the type of diabetes. Methods: We prospectively studied the maternal characteristics of all neonates who were born in our perinatal center and were treated in our department during the period 1996-2007. Infants of diabetic mothers were classified in three groups: Group A: mothers with preexisting diabetes, Group B: mothers with gestational diabetes, managed with insulin, Group C: mothers with gestational diabetes, managed with diet. Non diabetic mothers served as control. Results: Overall, 20.643 live neonates from 19.791 pregnancies were studied. Of them, 852 were complicated by diabetes. The incidence of DP was 1.86% from 1996 to 2000 and 5.57% from 2001 to 2007. Maternal-neonatal characteristics are shown in the table (*p< 0.001). Table Conclusions: The incidence of DP increased during the last 6 years. The prevalence of IVF is significantly elevated only in gestational diabetes treated with insulin. Also, in term neonates, birth weight was significantly higher only in women with preexisiting diabetes. These results, however, need to be confirmed in other studies.