Stable HLA antibodies following sustained CD19+ cell depletion implicate a long-lived plasma cell source

Stable HLA antibodies following sustained CD19+ cell depletion implicate a long-lived plasma cell source

•HLA-specific alloantibodies can be maintained despite profound CD19+ cell aplasia, likely due to production by CD19− plasma cells.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Blood advances 2020-09, Vol.4 (18), p.4292-4295
Hauptverfasser: Zhang, Zheng, Schuster, Stephen J., Lacey, Simon F., Milone, Michael C., Monos, Dimitri, Bhoj, Vijay G.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Antigens, CD19
Hematology
Life Sciences & Biomedicine
Plasma Cells
Science & Technology
Stimulus Report
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:•HLA-specific alloantibodies can be maintained despite profound CD19+ cell aplasia, likely due to production by CD19− plasma cells.
ISSN:2473-9529
2473-9537
DOI:10.1182/bloodadvances.2020002435