Reduced Intensity Haploidentical Bone Marrow Transplantation in Adults with Severe Sickle Cell Disease: BMT CTN 1507

Background: Allogeneic hematopoietic stem-cell transplantation has curative potential for sickle cell disease (SCD). Event-free survival (EFS) in children with SCD is >90% after a bone marrow transplant (BMT) from a myeloablative matched sibling donor (MSD). Unfortunately,

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Bibliographische Detailangaben
Veröffentlicht in:	Blood 2023-11, Vol.142 (Supplement 2), p.LBA-4-LBA-4
Hauptverfasser:	Kassim, Adetola A., Walters, Mark C., Eapen, Mary, Ritzau, Nicole, Smith, Madoc, Solh, Melhem M., McKinney, Christopher, Nieder, Michael, Ross, Maureen, Kent, Michael, Abusin, Ghada, Mallhi, Kanwaldeep K., Silva, Jorge Galvez, Shaughnessy, Paul, Kanter, Julie, Haines, Hilary, Farah, Rafic J, Khaled, Yasser, Abraham, Allistair, Bollard, Catherine M., Cooke, Kenneth R., de La Fuente, Josu, Hanna, Rabi, Horowitz, Mary M., Jordan, Lori C, Krishnamurti, Lakshmanan, Leifere, Eric, Mahadeo, Kris Michael, Shenoy, Shalini, Ritzau, Nicole M., DeBaun, Michael R., Brodsky, Robert A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Background: Allogeneic hematopoietic stem-cell transplantation has curative potential for sickle cell disease (SCD). Event-free survival (EFS) in children with SCD is >90% after a bone marrow transplant (BMT) from a myeloablative matched sibling donor (MSD). Unfortunately,
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood-2023-192022