Ultra-Hypofractionated Involved Site Radiation Therapy (ISRT) As Salvage or Bridging Therapy in Aggressive Non-Hodgkin Lymphomas

Ultra-Hypofractionated Involved Site Radiation Therapy (ISRT) As Salvage or Bridging Therapy in Aggressive Non-Hodgkin Lymphomas

Introduction: Conventional fractionated radiation treatment (RT) to a total dose of 40-50 Gy in 20-25 fractions is typically recommended in the ‘definitive’ intent treatment of aggressive chemorefractory non-Hodgkin lymphoma. However, during the time of COVID-19, recommendations for hypofractionated...

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.6283-6283
Hauptverfasser: Veeramachaneni, Tanooha, Li, Xingzhe, Desai, Neil, Wolfe, Heather R, Yilmaz, Elif, Awan, Farrukh T., Collins, Robert H., Timmerman, Robert, Ramakrishnan Geethakumari, Praveen, Kumar, Kiran Achut
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Sprache:eng
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Zusammenfassung:Introduction: Conventional fractionated radiation treatment (RT) to a total dose of 40-50 Gy in 20-25 fractions is typically recommended in the ‘definitive’ intent treatment of aggressive chemorefractory non-Hodgkin lymphoma. However, during the time of COVID-19, recommendations for hypofractionated courses (5-13 fractions) arose (Yahalom et al Blood 2020) as modern radiation techniques should allow similar total doses to be delivered safely in far fewer fractions. Our aim is to evaluate the outcomes and toxicities of ultra-hypofractionated (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2023-191089