Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

Plasma Proteomic Signature Predicts Risk of Myeloid Neoplasm

Introduction The presence of clonally expanded mutant hematopoietic stem cells, clonal hematopoiesis (CH) is known to predispose to hematologic malignancy, particularly myeloid neoplasms (MN). However, the overall risk of developing MNs among individuals with CH is low (

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Veröffentlicht in:Blood 2023-11, Vol.142 (Supplement 1), p.940-940
Hauptverfasser: Beeler, J. Scott, Tran, Duc, Liu, Jie, Xin, Zilan, Wiley, Brian, Chan, Irenaeus C.C., Kramer, Michael H., Batchi-Bouyou, Armel L., Zong, Xiaoyu, Walter, Matthew J., Chlamydas, Sarantis, Ferraro, Francesca, Oh, Stephen T., Busby, Ben, Link, Daniel C., Cao, Yin, Bolton, Kelly L.
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Sprache:eng
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Zusammenfassung:Introduction The presence of clonally expanded mutant hematopoietic stem cells, clonal hematopoiesis (CH) is known to predispose to hematologic malignancy, particularly myeloid neoplasms (MN). However, the overall risk of developing MNs among individuals with CH is low (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2023-190857