The Prognostic Impact of t(14;16) in Multiple Myeloma: A Multicenter Retrospective Study of 213 Patients. Is It Time to Revise the Revised ISS?

Introduction One of the strongest predictors of outcome in multiple myeloma (MM) patients are the intrinsic genetic abnormalities in the malignant plasma cells. t(14;16)(q32;q23) deregulates the c-musculoaponeurotic fibrosarcoma (c-MAF) oncogene. Due to the relative rarity of t(14;16) [

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 2018-11, Vol.132 (Supplement 1), p.4452-4452
Hauptverfasser:	Jurczyszyn, Artur, Goldman-Mazur, Sarah, Castillo, Jorge J., Waszczuk-Gajda, Anna, Grząśko, Norbert, Radocha, Jakub, Bittrich, Max, Gozzetti, Alessandro, Usnarska-Zubkiewicz, Lidia, Hus, Iwona, Yee, Andrew J, Jayabalan, David S, Niesvizky, Ruben, Kelman, Julia, Coriu, Daniel, Rosinol Dachs, Laura, Szukalski, Łukasz, Dávila, Julio, Gonzalez De La Calle, Veronica, Jamroziak, Krzysztof, Avivi, Irit, Cohen, Yael C, Suska, Anna, Chappell, Aimee, Madduri, Deepu, Chhabra, Saurabh, Kleman, Ariel, Hari, Parameswaran, Robak, Paweł, Gentile, Massimo, Kozłowska, Izabela, Goldberg, Stuart L., Vesole, David H
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Introduction One of the strongest predictors of outcome in multiple myeloma (MM) patients are the intrinsic genetic abnormalities in the malignant plasma cells. t(14;16)(q32;q23) deregulates the c-musculoaponeurotic fibrosarcoma (c-MAF) oncogene. Due to the relative rarity of t(14;16) [
ISSN:	0006-4971 1528-0020
DOI:	10.1182/blood-2018-99-115971