Preliminary Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) MM17 Trial: Response Adaptive Salvage Treatment with Carfilzomib-Thalidomide-Dexamethasone (KTd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy

Preliminary Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) MM17 Trial: Response Adaptive Salvage Treatment with Carfilzomib-Thalidomide-Dexamethasone (KTd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy

Background Data from the Australian and New Zealand (ANZ) Myeloma and Related Diseases Registry (MRDR) shows that 85% of newly diagnosed multiple myeloma (NDMM) patients (pts) in ANZ are induced with bortezomib(V)-containing therapies, predominantly triplets of V-cyclophosphamide-dexamethasone (VCD)...

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Veröffentlicht in:Blood 2018-11, Vol.132 (Supplement 1), p.3279-3279
Hauptverfasser: Spencer, Andrew, Quach, Hang, Horvath, Noemi, Kerridge, Ian H., Yuen, Flora, Lee, Edwin Sze-Hung, Morris, Edward S., Kalff, Anna, Bergin, Krystal, Sirdesai, Shreerang, Gorniak, Malgorzata, Mithraprabhu, Sridurga, Khong, Tiffany, Reynolds, John
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Sprache:eng
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Zusammenfassung:Background Data from the Australian and New Zealand (ANZ) Myeloma and Related Diseases Registry (MRDR) shows that 85% of newly diagnosed multiple myeloma (NDMM) patients (pts) in ANZ are induced with bortezomib(V)-containing therapies, predominantly triplets of V-cyclophosphamide-dexamethasone (VCD). Of these, 15% demonstrate treatment failure - either a sub-optimal response (
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2018-99-113982