SENSITIVITY IN ELECTRON MICROSCOPE AUTORADIOGRAPHY I. THE EFFECT OF RADIATION DOSE

Sensitivity in electron microscope autoradiography using Ilford L4 emulsion was shown to be affected by radiation dose (i.e., number of decays in test specimen per unit surface area). The sensitivity tended to be higher with lower doses. This dose dependence was most marked with Microdol X and least...

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Veröffentlicht in:	J. Histochem. Cytochem. 20: No. 6, 425-34(1972) 425-34(1972), 1972-06, Vol.20 (6), p.425-434
Hauptverfasser:	SALPETER, MIRIAM M, SZABO, MARIA
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Sprache:	eng
Schlagworte:	Absorption Acrylic Resins Ascorbic Acid AUTORADIOGRAPHY AUTORADIOGRAPHY/sensitivity of electron microscope, effect of radiation dose on CALIBRATION CALIBRATION STANDARDS DEVELOPERS DOSE- RESPONSE RELATIONSHIPS ELECTRON MICROSCOPES ELECTRON MICROSCOPES/calibration procedures for autoradiography Emulsions Gold Methods Microscopy, Electron N46110 -Instrumentation-Radiation Detection Instruments- General Detectors & Monitors NUCLEAR EMULSIONS NUCLEAR EMULSIONS/sensitivity of Ilford L4, effect of developer on dose dependence of Phenols PHOTOGRAPHIC FILMS PHOTOGRAPHY Radiation Dosage SENSITIVITY Sulfites Thiocyanates Tritium
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container_end_page	434
container_issue	6
container_start_page	425
container_title	J. Histochem. Cytochem. 20: No. 6, 425-34(1972)
container_volume	20
creator	SALPETER, MIRIAM M SZABO, MARIA
description	Sensitivity in electron microscope autoradiography using Ilford L4 emulsion was shown to be affected by radiation dose (i.e., number of decays in test specimen per unit surface area). The sensitivity tended to be higher with lower doses. This dose dependence was most marked with Microdol X and least with gold latensification-Elon ascorbic acid development. Possible consequences for quantitation in electron microscope autoradiography are discussed.
doi_str_mv	10.1177/20.6.425
format	Article
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Possible consequences for quantitation in electron microscope autoradiography are discussed.</description><identifier>ISSN: 0022-1554</identifier><identifier>EISSN: 1551-5044</identifier><identifier>DOI: 10.1177/20.6.425</identifier><identifier>PMID: 5032979</identifier><language>eng</language><publisher>London, England: Histochemical Soc</publisher><subject>Absorption ; Acrylic Resins ; Ascorbic Acid ; AUTORADIOGRAPHY ; AUTORADIOGRAPHY/sensitivity of electron microscope, effect of radiation dose on ; CALIBRATION ; CALIBRATION STANDARDS ; DEVELOPERS ; DOSE- RESPONSE RELATIONSHIPS ; ELECTRON MICROSCOPES ; ELECTRON MICROSCOPES/calibration procedures for autoradiography ; Emulsions ; Gold ; Methods ; Microscopy, Electron ; N46110 -Instrumentation-Radiation Detection Instruments- General Detectors & Monitors ; NUCLEAR EMULSIONS ; NUCLEAR EMULSIONS/sensitivity of Ilford L4, effect of developer on dose dependence of ; Phenols ; PHOTOGRAPHIC FILMS ; PHOTOGRAPHY ; Radiation Dosage ; SENSITIVITY ; Sulfites ; Thiocyanates ; Tritium</subject><ispartof>J. 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Cytochem. 20: No. 6, 425-34(1972), 1972-06, Vol.20 (6), p.425-434</ispartof><rights>1972, THE HISTOCHEMICAL SOCIETY, INC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3145-2c9571b0abbd2309d53a0fdaf2861208c9953639bd4d8611d62d2295a09bb1d93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/20.6.425$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/20.6.425$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,885,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5032979$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/4586562$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>SALPETER, MIRIAM M</creatorcontrib><creatorcontrib>SZABO, MARIA</creatorcontrib><creatorcontrib>Cornell Univ., Ithaca, N. 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Possible consequences for quantitation in electron microscope autoradiography are discussed.</description><subject>Absorption</subject><subject>Acrylic Resins</subject><subject>Ascorbic Acid</subject><subject>AUTORADIOGRAPHY</subject><subject>AUTORADIOGRAPHY/sensitivity of electron microscope, effect of radiation dose on</subject><subject>CALIBRATION</subject><subject>CALIBRATION STANDARDS</subject><subject>DEVELOPERS</subject><subject>DOSE- RESPONSE RELATIONSHIPS</subject><subject>ELECTRON MICROSCOPES</subject><subject>ELECTRON MICROSCOPES/calibration procedures for autoradiography</subject><subject>Emulsions</subject><subject>Gold</subject><subject>Methods</subject><subject>Microscopy, Electron</subject><subject>N46110 -Instrumentation-Radiation Detection Instruments- General Detectors & Monitors</subject><subject>NUCLEAR EMULSIONS</subject><subject>NUCLEAR EMULSIONS/sensitivity of Ilford L4, effect of developer on dose dependence of</subject><subject>Phenols</subject><subject>PHOTOGRAPHIC FILMS</subject><subject>PHOTOGRAPHY</subject><subject>Radiation Dosage</subject><subject>SENSITIVITY</subject><subject>Sulfites</subject><subject>Thiocyanates</subject><subject>Tritium</subject><issn>0022-1554</issn><issn>1551-5044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkFFrgzAUhcPY6LpusD8wkMFgL7okGm0exWordE1RO9hTiEZbR1uLaZH9-6VY-rSnC-d898A5ADwjaCHkeR8YWq7lYHIDhogQZBLoOLdgCCHGphace_Cg1A-EyHHIeAAGBNqYenQIkjRcpHEWf8XZtxEvjHAeBlnCFsZnHCQsDdgyNPxVxhJ_ErNp4i9nGrOMbBYaYRRp1mCRcTb9LNZfE5aGj-CuEltVPl3uCKyiMAtm5pxN48Cfm4WNHGLighIP5VDkucQ2pJLYAlZSVHjsIgzHBaXEdm2aS0dqBUkXS4wpEZDmOZLUHoHXPrdRx5qroj6WxaZo9vuyOHJd0yUu1tB7DxVto1RbVvzQ1jvR_nIE-Xk6jiF3uZ5Ooy89ejjlu1JewctW2n_rfSXWJf9pTu1e1_sv58Jt6vWmq9uSq53YbnUq4l3XXbk_5bJ30A</recordid><startdate>197206</startdate><enddate>197206</enddate><creator>SALPETER, MIRIAM M</creator><creator>SZABO, MARIA</creator><general>Histochemical Soc</general><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>197206</creationdate><title>SENSITIVITY IN ELECTRON MICROSCOPE AUTORADIOGRAPHY I. THE EFFECT OF RADIATION DOSE</title><author>SALPETER, MIRIAM M ; SZABO, MARIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3145-2c9571b0abbd2309d53a0fdaf2861208c9953639bd4d8611d62d2295a09bb1d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Absorption</topic><topic>Acrylic Resins</topic><topic>Ascorbic Acid</topic><topic>AUTORADIOGRAPHY</topic><topic>AUTORADIOGRAPHY/sensitivity of electron microscope, effect of radiation dose on</topic><topic>CALIBRATION</topic><topic>CALIBRATION STANDARDS</topic><topic>DEVELOPERS</topic><topic>DOSE- RESPONSE RELATIONSHIPS</topic><topic>ELECTRON MICROSCOPES</topic><topic>ELECTRON MICROSCOPES/calibration procedures for autoradiography</topic><topic>Emulsions</topic><topic>Gold</topic><topic>Methods</topic><topic>Microscopy, Electron</topic><topic>N46110 -Instrumentation-Radiation Detection Instruments- General Detectors & Monitors</topic><topic>NUCLEAR EMULSIONS</topic><topic>NUCLEAR EMULSIONS/sensitivity of Ilford L4, effect of developer on dose dependence of</topic><topic>Phenols</topic><topic>PHOTOGRAPHIC FILMS</topic><topic>PHOTOGRAPHY</topic><topic>Radiation Dosage</topic><topic>SENSITIVITY</topic><topic>Sulfites</topic><topic>Thiocyanates</topic><topic>Tritium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SALPETER, MIRIAM M</creatorcontrib><creatorcontrib>SZABO, MARIA</creatorcontrib><creatorcontrib>Cornell Univ., Ithaca, N. 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Cytochem</addtitle><date>1972-06</date><risdate>1972</risdate><volume>20</volume><issue>6</issue><spage>425</spage><epage>434</epage><pages>425-434</pages><issn>0022-1554</issn><eissn>1551-5044</eissn><abstract>Sensitivity in electron microscope autoradiography using Ilford L4 emulsion was shown to be affected by radiation dose (i.e., number of decays in test specimen per unit surface area). The sensitivity tended to be higher with lower doses. This dose dependence was most marked with Microdol X and least with gold latensification-Elon ascorbic acid development. Possible consequences for quantitation in electron microscope autoradiography are discussed.</abstract><cop>London, England</cop><pub>Histochemical Soc</pub><pmid>5032979</pmid><doi>10.1177/20.6.425</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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source	MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SAGE Complete A-Z List; Free Full-Text Journals in Chemistry
subjects	Absorption Acrylic Resins Ascorbic Acid AUTORADIOGRAPHY AUTORADIOGRAPHY/sensitivity of electron microscope, effect of radiation dose on CALIBRATION CALIBRATION STANDARDS DEVELOPERS DOSE- RESPONSE RELATIONSHIPS ELECTRON MICROSCOPES ELECTRON MICROSCOPES/calibration procedures for autoradiography Emulsions Gold Methods Microscopy, Electron N46110 -Instrumentation-Radiation Detection Instruments- General Detectors & Monitors NUCLEAR EMULSIONS NUCLEAR EMULSIONS/sensitivity of Ilford L4, effect of developer on dose dependence of Phenols PHOTOGRAPHIC FILMS PHOTOGRAPHY Radiation Dosage SENSITIVITY Sulfites Thiocyanates Tritium
title	SENSITIVITY IN ELECTRON MICROSCOPE AUTORADIOGRAPHY I. THE EFFECT OF RADIATION DOSE
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