Secondary Metabolites from Clerodendrum Chinense

Chemical studies carried out on Clerodendrum chinense yielded three new compounds including the steroid (22E, 24S)-stigmasta-4, 22, 25-trien-3-one (1), the flavone glycoside 7, 8, 4′-trihydroxyflavone-6-O-β-D-glucuronopyranoside (2) and the epimeric neo-clerodane 14, 15-dihydro-15ξ-hydroxyclerodendr...

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Veröffentlicht in:Natural product communications 2008-11, Vol.3 (11)
Hauptverfasser: Layne, Tanya H., Reynolds, William F., McLean, Stewart, Tinto, Winston F.
Format: Artikel
Sprache:eng
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Zusammenfassung:Chemical studies carried out on Clerodendrum chinense yielded three new compounds including the steroid (22E, 24S)-stigmasta-4, 22, 25-trien-3-one (1), the flavone glycoside 7, 8, 4′-trihydroxyflavone-6-O-β-D-glucuronopyranoside (2) and the epimeric neo-clerodane 14, 15-dihydro-15ξ-hydroxyclerodendrin A (3). Two acetylated derivatives of compound 3-, 2α-acetoxy-14, 15-dihydro-15ξ-hydroxyclerodendrin A (4) and 2α-acetoxy-14, 15-dihydro-15ξ-methoxyclerodendrin A (5) were also prepared, which have not been reported previously. The structure of each compound was elucidated by spectroscopic means.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X0800301108