Platelet rich plasma for primary macular hole: A case series

Objective To evaluate the anatomical and functional macular results and rate of complications following surgical treatment of primary macular hole (MH) with autologous platelet rich plasma (a-PRP) use. Design retrospective, interventional, non-randomized case series Partecipants and methods A cohort...

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Veröffentlicht in:European journal of ophthalmology 2024-11, Vol.34 (6), p.1984-1990
Hauptverfasser: Parisi, Guglielmo, Gelormini, Francesco, Ricardi, Federico, Borrelli, Enrico, Parisi, Francesca, Belluardo, Giuseppe, Azzaro, Laura, Marolo, Paola, D’antico, Sergio, Salafia, Marika, Reibaldi, Michele
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Sprache:eng
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Zusammenfassung:Objective To evaluate the anatomical and functional macular results and rate of complications following surgical treatment of primary macular hole (MH) with autologous platelet rich plasma (a-PRP) use. Design retrospective, interventional, non-randomized case series Partecipants and methods A cohort of 9 consecutive patients from January 1, 2019 to August 31, 2021 who underwent vitrectomy with a-PRP use for primary MH were included. Anatomical results based on spectral domain- optical coherence tomography (SD-OCT) and visual acuity were analyzed. Results 10 pseudophakic eye of 9 patients were enrolled. Six patients were female and three patients were male. The mean age was 69.9 years ± 1.48. The baseline MH minimum diameter was 486.1 μm ± 37.1, and mean pre operative best-corrected visual acuity (BCVA) was 0.91 ± 0.03 logMAR (Snellen equivalent 20/160). Mean 1 month post operative BCVA was 0.81 ± 0.57 logMAR (Snellen equivalent 20/130; p = 1.000); mean 3 month post operative BCVA was 0.66 ± 0.04 logMAR (Snellen equivalent 20/90; p = 0.006); mean 6 month post operative BCVA was 0.6 ± 0.04 logMAR (Snellen equivalent 20/80; p 
ISSN:1120-6721
1724-6016
DOI:10.1177/11206721241234419