The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond

The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond

Mass spectrometry (MS) offers a label-free, direct-detection method, in contrast to fluorescent or colorimetric methodologies. Over recent years, solid-phase extraction–based techniques, such as the Agilent RapidFire system, have emerged that are capable of analyzing samples in

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Bibliographische Detailangaben
Veröffentlicht in:Journal of biomolecular screening 2016-02, Vol.21 (2), p.176-186
Hauptverfasser: Haslam, Carl, Hellicar, John, Dunn, Adrian, Fuetterer, Arne, Hardy, Neil, Marshall, Peter, Paape, Rainer, Pemberton, Michelle, Resemannand, Anja, Leveridge, Melanie
Format: Artikel
Sprache:eng
Schlagworte:
Acetylcholinesterase - chemistry
Chromatography, Liquid - methods
High-Throughput Screening Assays - methods
Histone Demethylases - chemistry
Peptides - chemistry
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
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Beschreibung
Zusammenfassung:Mass spectrometry (MS) offers a label-free, direct-detection method, in contrast to fluorescent or colorimetric methodologies. Over recent years, solid-phase extraction–based techniques, such as the Agilent RapidFire system, have emerged that are capable of analyzing samples in
ISSN:1087-0571
2472-5552
1552-454X
DOI:10.1177/1087057115608605