HPLC Studio: A Novel Software Utility to Perform HPLC Chromatogram Comparison for Screening Purposes
A new tool, HPLC Studio, was developed for the comparison of high-performance liquid chromatography (HPLC) chromatograms from microbial extracts. The new utility makes it possible to create a virtual chromatogram by mixing up to 20 individual chromatograms. The virtual chromatogram is the first step...
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Veröffentlicht in: | Journal of biomolecular screening 2003-06, Vol.8 (3), p.305-315 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A new tool, HPLC Studio, was developed for the comparison of high-performance liquid chromatography (HPLC) chromatograms from microbial extracts. The new utility makes it possible to create a virtual chromatogram by mixing up to 20 individual chromatograms. The virtual chromatogram is the first step in establishing a ranking of the microbial fermentation conditions based on either the area or diversity of HPLC peaks. The utility was used to maximize the diversity of secondary metabolites tested from a microorganism and therefore increase the chances of finding new lead compounds in a drug discovery program. (Journal of Biomolecular Screening 2003:305-315) |
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ISSN: | 1087-0571 2472-5552 1552-454X |
DOI: | 10.1177/1087057103008003008 |