FEV 1 /FVC Severity Stages for Chronic Obstructive Pulmonary Disease

The diagnosis of chronic obstructive pulmonary disease (COPD) is based on a low FEV /FVC ratio, but the severity of COPD is classified using FEV % predicted (ppFEV ). To test a new severity classification scheme for COPD using FEV /FVC ratio, a more robust measure of airflow obstruction than ppFEV ....

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2023-09, Vol.208 (6), p.676-684
Hauptverfasser:	Bhatt, Surya P, Nakhmani, Arie, Fortis, Spyridon, Strand, Matthew J, Silverman, Edwin K, Sciurba, Frank C, Bodduluri, Sandeep
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Emphysema Forced Expiratory Volume Humans Lung Pulmonary Disease, Chronic Obstructive Pulmonary Emphysema Quality of Life Spirometry Vital Capacity
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Zusammenfassung:	The diagnosis of chronic obstructive pulmonary disease (COPD) is based on a low FEV /FVC ratio, but the severity of COPD is classified using FEV % predicted (ppFEV ). To test a new severity classification scheme for COPD using FEV /FVC ratio, a more robust measure of airflow obstruction than ppFEV . In COPDGene (Genetic Epidemiology of COPD) ( = 10,132), the severity of airflow obstruction was categorized by Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 1-4 (ppFEV of ⩾80%, ⩾50-80%, ⩾30-50%, and
ISSN:	1073-449X 1535-4970
DOI:	10.1164/rccm.202303-0450OC