A case of cytomegalovirus enterocolitis in a healthy subject

Male, in his 20s chief complaint fever and diarrhea. Blood tests showed WBC15,600 and CRP4.9, and CT scan showed thickening of the colonic wall in primary care clinic. Blood tests in our hospital showed WBC12,130, CRP5.0, CMV-IgM13.4, IgG93.7 and CMV antigenemia negative. CT scan showed splenic infarction, wall thickening of the ascending to transverse colon. Colonoscopy revealed multiple erosions in the terminal ileum and scattered erosions and shallow ulcers in the right-sided colon. Histopathology showed chronic inflammatory cell infiltrates, with no apparent nuclear inclusion bodies; CMV immunostaining showed plasma cells with positive cytoplasm, as well as large cells with indistinct nuclear morphology and positive whole cells. Diagnosis of enteritis associated with cytomegalovirus infection. We experienced a case of cytomegalovirus enteritis in a healthy subject.