Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents

Summary The DAPT score is a recently-proposed decision tool for guiding optimal duration of dual antiplatelet therapy (DAPT). It showed modest accuracy in prior derivation and validation cohorts of patients with ≥12 months DAPT. This study was aimed to evaluate the validity of the DAPT score in a co...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Thrombosis and haemostasis 2017, Vol.117 (10), p.1989-1999
Hauptverfasser:	Harada, Yukinori, Michel, Jonathan, Lohaus, Raphaela, Mayer, Katharina, Emmer, Roberto, Lena Lahmann, Anna, Colleran, Roisin, Giacoppo, Daniele, Wolk, Annabelle, Berg, Jurrien M. ten, Neumann, Franz-Josef, Han, Yaling, Adriaenssens, Tom, Tölg, Ralph, Seyfarth, Melchior, Maeng, Michael, Zrenner, Bernhard, Jacobshagen, Claudius, Wöhrle, Jochen, Kufner, Sebastian, Morath, Tanja, Ibrahim, Tareq, Bernlochner, Isabell, Fischer, Marcus, Schunkert, Heribert, Laugwitz, Karl-Ludwig, Mehilli, Julinda, A. Byrne, Robert, Kastrati, Adnan, Schulz-Schüpke, Stefanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aspirin - administration & dosage Atherosclerosis and Ischaemic Disease Clinical Decision-Making Coronary Disease - diagnosis Coronary Disease - mortality Coronary Disease - therapy Coronary Thrombosis - etiology Decision Support Techniques Double-Blind Method Drug Administration Schedule Drug Therapy, Combination Drug-Eluting Stents Female Hemorrhage - chemically induced Humans Kaplan-Meier Estimate Male Myocardial Infarction - etiology Percutaneous Coronary Intervention - adverse effects Percutaneous Coronary Intervention - instrumentation Percutaneous Coronary Intervention - mortality Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - adverse effects Predictive Value of Tests Proportional Hazards Models Prosthesis Design Reproducibility of Results Risk Factors Stroke - etiology Ticlopidine - administration & dosage Ticlopidine - adverse effects Ticlopidine - analogs & derivatives Time Factors Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Summary The DAPT score is a recently-proposed decision tool for guiding optimal duration of dual antiplatelet therapy (DAPT). It showed modest accuracy in prior derivation and validation cohorts of patients with ≥12 months DAPT. This study was aimed to evaluate the validity of the DAPT score in a cohort of patients with 6 or 12 months DAPT after implantation of predominantly second-generation drug-eluting stents. We analyzed data of patients enrolled in the ISAR-SAFE trial. Patients were classified into low (
ISSN:	0340-6245 2567-689X
DOI:	10.1160/TH17-02-0101