Pharmacologic Modulation of Acute Ocular Inflammation

Pharmacologic Modulation of Acute Ocular Inflammation

Modulation of signal transduction at the surface of inflammatory cells appears to influence acute inflammation. Adenosine, a well-known chemical messenger, inhibits the production of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal’s’ antig...

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Veröffentlicht in:Ophthalmic research 2009-12, Vol.20 (4), p.220-226
Hauptverfasser: Marak, Jr, George E., De Kozak, Yvonne, Faure, Jean-Pierre, Rao, Narsing A., Romero, Jorge L., Ward, Peter A., Till, Gerd O.
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Sprache:eng
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Zusammenfassung:Modulation of signal transduction at the surface of inflammatory cells appears to influence acute inflammation. Adenosine, a well-known chemical messenger, inhibits the production of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal’s’ antigen, treatment with adenosine produced a marked reduction in the expected inflammation.
ISSN:0030-3747
1423-0259
DOI:10.1159/000266646