Nucleotide Sequence, Chromosome Localization, and Evolutionary Conservation of a Serine Hydroxymethyltransferase-Processed Pseudogene

The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human heredity 1997-05, Vol.47 (3), p.125-130
Hauptverfasser:	Devor, Eric J., Dill-Devor, Rebecca M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Chromosome Mapping Chromosomes, Human, Pair 1 Conserved Sequence - genetics Cytosol Fundamental and applied biological sciences. Psychology Genes. Genome Glycine Hydroxymethyltransferase - genetics Humans Molecular and cellular biology Molecular genetics Molecular Sequence Data Original Paper Primates Pseudogenes - genetics Sequence Analysis, DNA Sequence Homology, Nucleic Acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of this pseudogene among several species of nonhuman primate indicates a relatively high degree of sequence conservation.
ISSN:	0001-5652 1423-0062
DOI:	10.1159/000154400