Ex vivo Evaluation of Tono-Pen and Pneumotonometry in Cat Eyes
Purpose: To evaluate the validity and intraobserver reliability of intraocular pressure (IOP) measurements with both pneumotonometry and the Tono-Pen in a closed ex vivo system in cat eyes. Methods: IOP was increased step by step in 5 enucleated cat eyes, while taking IOP measurements with the Tono-...
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Veröffentlicht in: | Ophthalmic research 2006-01, Vol.38 (1), p.13-18 |
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Sprache: | eng |
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Zusammenfassung: | Purpose: To evaluate the validity and intraobserver reliability of intraocular pressure (IOP) measurements with both pneumotonometry and the Tono-Pen in a closed ex vivo system in cat eyes. Methods: IOP was increased step by step in 5 enucleated cat eyes, while taking IOP measurements with the Tono-Pen and pneumotonometry. The outcomes were compared to readings of a digital manometer simultaneously measuring the actual pressure in the anterior chamber. Results: Pneumotonometry overestimated IOP below 15 mm Hg and underestimated pressures above 20 mm Hg. Tono-Pen tonometry considerably underestimated IOP over the whole spectrum in all of the eyes tested. The pneumotonometer was identified as the more valid and reliable instrument for cat eyes. Conclusion: Both tonometers are clinically useful tools to assess IOP for glaucoma studies using a cat animal model. However, one has to consider underestimation of IOP in the upper ranges. A correction formula can be used to calculate the actual IOP. |
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ISSN: | 0030-3747 1423-0259 |
DOI: | 10.1159/000088492 |