Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also ma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cytogenetic and genome research 2000-01, Vol.88 (1-2), p.38-40
Hauptverfasser:	Murthy, S.S., Tosolini, A., Taguchi, T., Testa, J.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt protein AKT3 gene AKT3 protein Animals Biological and medical sciences chromosome 1 chromosome 13 Chromosomes, Human, Pair 1 - genetics Cloning, Molecular Fibroblasts Fundamental and applied biological sciences. Psychology Genes. Genome Humans In Situ Hybridization, Fluorescence Lymphocytes Mice Molecular and cellular biology Molecular genetics Multigene Family - genetics Oncogene Proteins - genetics Physical Chromosome Mapping protein kinase B Protein-Serine-Threonine Kinases - genetics Proto-Oncogene Proteins c-akt Rats Sequence Homology, Amino Acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24→q26 and mouse chromosome 1H4–6 by FISH.
ISSN:	1424-8581 0301-0171 1424-859X
DOI:	10.1159/000015481