Abstract B121: HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplant cyclophosphamide improves clinical outcomes for racial and ethnic minority patients with hematologic malignancies

Introduction: Racial and ethnic disparities exist in three areas related to hematopoietic cell transplantation (HCT): donor availability, access, and post-HCT outcomes. A significant barrier to access to HCT for patients (pts) of racial or ethnic minorities (REM) is the limited availability of fully...

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Veröffentlicht in:Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2023-01, Vol.32 (1_Supplement), p.B121-B121
Hauptverfasser: Jimenez, Antonio M. Jimenez, Iyer, Sunil, Komanduri, Krishna, Brown, Samantha, Wang, Trent, Chinapen, Stephanie, Pereira, Denise, Devlin, Sean, Goodman, Mark, Beitinjaneh, Amer, Sauter, Craig, Lekakis, Lazaros, Perales, Miguel Angel, Ponce, Doris, Shaffer, Brian
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Sprache:eng
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Zusammenfassung:Introduction: Racial and ethnic disparities exist in three areas related to hematopoietic cell transplantation (HCT): donor availability, access, and post-HCT outcomes. A significant barrier to access to HCT for patients (pts) of racial or ethnic minorities (REM) is the limited availability of fully matched donors (i.e., grafts matched at HLA-A, -B, -C, and -DRB1 loci) in volunteer registries. While mismatched unrelated donor (MMUD) grafts (i.e.,
ISSN:1538-7755
1538-7755
DOI:10.1158/1538-7755.DISP22-B121