Abstract LB082: Prostate cancer incidence and mortality in the United States, 2000-2016

Background/Purpose Prostate cancer (PC) is the second most common and deadly cancer among men in the United States. In general, incidence rate of prostate cancer has declined while mortality rate has increased over the past 15 years. The purpose of this study is to assess the incidence and mortality rates of this cancer according to race/ethnicity from 2000-2016. Methods We obtained data from the Surveillance, Epidemiology and End Results (SEER) 18 program to calculate incidence and mortality rates by race/ethnicity from 2000 to 2016. The Annual Percent Change (APC) was also obtained for incidence and mortality rates by race/ethnicity. Results From 2000-2016, the overall incidence rate has decreased significantly from 77.4 to 49.1 per 100,000 (APC = -3.1). Asian and Pacific Islander had the highest decline in incidence rate from 44.4 to 23.4 per 100,000 whereas African-American had the lowest decline from 113.3 to 72.4 per 100,000 (APC -4.4 vs -2.9 respectively). Conversely, the death rate has increased substantially, particularly among White and Black (APC = 8.6 vs 6.6). However, African-Americans still have a disproportionate mortality rate compared to White (46.5 vs 28.8 per 100,000). Conclusion African-Americans are still suffering disproportionately from the PC. There is a need to implement public health interventions to improve PC screening among African-Americans, and examine additional factors that may contribute to the burden of this cancer among African-Americans. Citation Format: Michael Rutalira Koko, Rasaki Aranmolate, Raza Z. Shah, Glodi Mutamba. Prostate cancer incidence and mortality in the United States, 2000-2016 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr LB082.