Abstract 276: Retrospective analysis of epidemiological variants of malignancies in Sokoto, Northwestern Nigeria

Background: The burden of cancer in Nigeria is increasing. Information on incidence, prevalence, pattern, and high risk factors are essential for evaluation and cancer control. This report is a follow up from earlier previous report published in 2005 on cancers seen in Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto. Objectives: The aim of this study is to determine epidemiological variants of all malignancies seen from 1 January 2006 to 31 December 2015. Materials and Methods: This is a retrospective review of all malignancies seen at the Usmanu Danfodiyo University Teaching Hospital in Sokoto during the period 2006 to 2016. There was no restriction on gender or age groups. Mean, frequencies, percentages, and independent sample t-test were performed using SPSS version 21.0 for Windows. Significant level set at p < 0.05. Results: A total of 3933 cancer patients were seen during the ten-year period. There were more female malignancies (n=2260, 57.5%) compared to male malignancies (n=1673, 42.5%). The overall mean age (years) was 44.28, median age was 45.0, modal age was 50, and SD was 18.69; the age range was 1 to 99 years. Males (mean age 45.77, median age in male 50.0, modal age 60, and SD 21.03) were significantly older than females (mean age 43.18, median age 45.0, modal age 50, and SD 16.67). The adult malignancies account for 90.9% (n=3575) and childhood malignancies account for 9.1% (n=358). Overall, the ten most common malignancies were: breast 763 (19.4%), cervix 312 (7.9%), prostate 267 (6.8%), lymph node 248 (6.3%), skin 225 (5.7%), bladder 191 (4.9%), rectum 114 (2.9%), ovary 110 (2.8%), eye 97 (2.5%), soft tissue 95 (2.4%). In males, the ten most frequent malignancies were: prostate 267 (16.00%), bladder 160 (9.60%), skin 138 (8.20%), nasophraynx 87 (5.2%), lymph node 85 (5.10%), rectum 61 (3.60%), eye 55 (3.30%), salivary gland 38 (2.3%), larynx 37 (2.20%), and anal 37 (2.20%). In females, the ten most common malignancies were breast 731 (731%), cervix 302 (13.40%), lymph node 163 (7.20%), ovary 110 (4.90%), skin 87 (3.80%) endometrial 61 (2.70%), rectum 53 (2.30%), nasophraynx 45 (2.0%), soft tissue 43 (1.90%), and eye 42 (1.90%). Conclusion: Our study concludes that malignancies of the breast, cervix, and prostate are the three most common in our environment. These malignancies tend to present at younger age (less than 50 years of age) compared to other developing countries. Therefore, public education and well developed screeni