Abstract 2597: Prospective study of the relationship between coffee and tea with colorectal cancer risk: The PLCO cancer screening trial

Coffee and tea are commonly consumed and carry several potential anticancer components which could reduce the risk of colorectal cancer risk; however, the relationships of coffee and tea consumption with colorectal cancer risk remain unclear. We prospectively examined the relations of coffee and tea intake to colorectal cancer risk in 53,480 men and women in the intervention arm of the NCI-Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. The majority of these men and women (82.3%) received flexible sigmoidoscopy screening at baseline. Coffee and tea intakes were assessed by a food frequency questionnaire at study baseline. Six-hundred and twenty-two incident colorectal cancer cases were ascertained during a median follow-up of 11.4 years. Greater coffee intake was not associated with risk of colorectal cancer. The relative risks for