Abstract 2133: Identification of driver genes for amplification of the narrow amplicon at 2q11 present in oral cancers and pre-cancers

Abstract 2133: Identification of driver genes for amplification of the narrow amplicon at 2q11 present in oral cancers and pre-cancers

Genome-wide analysis of copy number aberrations in oral squamous cell carcinoma (SCC) and oral epithelial dysplasia, a pre-malignant lesion, by array CGH has revealed that the genomes of these cancers and pre-cancers frequently harbor narrow (∼3 Mb) regions of amplification. These amplicons are recu...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2010-04, Vol.70 (8_Supplement), p.2133-2133
Hauptverfasser: Lin, Mauting, Snijders, Antoine M., Bhattacharya, Aditi, Paquette, Jesse, Jordan, Richard C. K., Schmidt, Brian L., Albertson, Donna G.
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Sprache:eng
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Zusammenfassung:Genome-wide analysis of copy number aberrations in oral squamous cell carcinoma (SCC) and oral epithelial dysplasia, a pre-malignant lesion, by array CGH has revealed that the genomes of these cancers and pre-cancers frequently harbor narrow (∼3 Mb) regions of amplification. These amplicons are recurrent, but rare, being present in
ISSN:0008-5472
1538-7445
DOI:10.1158/1538-7445.AM10-2133