Thio-β-D-glucosides : Synthesis and Evaluation as Glycosidase Inhibitors and Activators
Structurally simple 1-thio-β-D-glucopyranosides were synthesized and tested as potential inhibitors toward several fungal glycosidases from Aspergillus oryzae and Penicillium canescens. Significant selective inhibition was observed for α- and β-glucosidases, while a weak to moderate activation for α...
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| Veröffentlicht in: | International Journal of Carbohydrate Chemistry 2014-12, Vol.2014 (2014), p.1-8 |
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| container_issue | 2014 |
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| container_title | International Journal of Carbohydrate Chemistry |
| container_volume | 2014 |
| creator | Samoshin, Andrey V. Dotsenko, Irina A. Samoshina, Nataliya M. Franz, Andreas H. Samoshin, Vyacheslav V. |
| description | Structurally simple 1-thio-β-D-glucopyranosides were synthesized and tested as potential inhibitors toward several fungal glycosidases from Aspergillus oryzae and Penicillium canescens. Significant selective inhibition was observed for α- and β-glucosidases, while a weak to moderate activation for α- and β-galactosidases. |
| doi_str_mv | 10.1155/2014/941059 |
| format | Article |
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| identifier | ISSN: 1687-9341 |
| ispartof | International Journal of Carbohydrate Chemistry, 2014-12, Vol.2014 (2014), p.1-8 |
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| language | eng |
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| source | Wiley Online Library Open Access; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| title | Thio-β-D-glucosides : Synthesis and Evaluation as Glycosidase Inhibitors and Activators |
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