The Skeletal Muscle Impedancemetric Characteristics as a Marker for Detection of Functional State of Organism

Previously it has been shown that cell hydration is a universal and extrasensitive marker for different environmental mediums and functional state of tissue and organism. The comparative study of cell hydration of different organs (brain cortex, liver, and skeletal muscle) at various experimental conditions (microstress, pathology, and different poisons) was realized. It was shown that among tissues of different organs muscle hydration is more sensitive to any change of functional state of organism and environmental medium. The study of correlation between tissue muscle hydration and double-frequency measurement impedance method indicated that the differences between muscle reactive conductivity measured at high frequency (HF) and low frequency (LF) (ΔGreactive) could be an adequate marker for detection of muscle hydration. The animal poisoning, stress, and pathology-induced tissue hydration were accompanied by increase in ΔGreactive. The observed close correlation between time-dependent tissue hydration and ΔGreactive in different environmental mediums can be a marker for detection of postmortal period as well as for characterizing environmental medium of the corpse.