A Graphene Stochastic Sensor for the Molecular Screening of TNF-α

A Graphene Stochastic Sensor for the Molecular Screening of TNF-α

A new stochastic sensor based on a graphene-platinum 3 matrix modified with protoporphyrin IX as electroactive material was optimized and used for the assay of tumor necrosis factor-alpha (TNF-α). The working concentration range of the stochastic sensor (1 to 100 pg/mL), as well as its sensitivity (...

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Veröffentlicht in:Journal of the Electrochemical Society 2015-01, Vol.162 (9), p.B245-B247
Hauptverfasser: Comnea-Stancu, Ionela Raluca, Stefan-van Staden, Raluca-Ioana, Biris, Alexandru Radu
Format: Artikel
Sprache:eng
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Zusammenfassung:A new stochastic sensor based on a graphene-platinum 3 matrix modified with protoporphyrin IX as electroactive material was optimized and used for the assay of tumor necrosis factor-alpha (TNF-α). The working concentration range of the stochastic sensor (1 to 100 pg/mL), as well as its sensitivity (4.44 × 108 s g/mL) and limit of quantification made possible its reliable utilization for screening test of children's cerebrospinal fluids for the tumor necrosis factor-alpha, with a recovery higher than 98.00%.
ISSN:0013-4651
1945-7111
DOI:10.1149/2.0931509jes