Utilizing as-synthesized Reduced Graphene Oxide Decorated with Mn 1−x Zn x Fe 2−y Cu y O 4 Doped Magnetic Nanoparticles for Efficient Electrochemical Sensing of Paracetamol

A highly sensitive sensor for paracetamol detection based on the copper and zinc doped manganese ferrite/reduced graphene oxide modified glassy carbon electrode (Mn 1−x Zn x Fe 2−y Cu y O 4 /rGO/GCE) is ameliorated. X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectrometry (FTIR), zeta-sizer, cyclic voltammetry, and electrochemical impedance spectroscopy are used to examine the structural, morphological, electroanalytical capability of the designed sensor. Results are correlated systematically for the copper/zinc doped manganese ferrite/reduced graphene oxide modified glassy carbon electrode and it is observed that the sensor exhibits two linear ranges as 5–9 μ mol l −1 and 9–200 μ mol l −1 under the optimized conditions. Doped composite-modified GCE demonstrates an exceptional limit of detection (LOD) (0.04 μ mol l −1 ) and the limit of quantification (LOQ) (0.15 μ mol l −1 ). The possible effect of structurally similar drugs on the anodic current response of paracetamol is evaluated. By analyzing the current generation of the actual pharmaceutical samples, the practical application of the manufactured sensor is assessed. Promising results demonstrated by modified GC electrode affirm its excellent analytical performance for the sensing of paracetamol with trace-level detection and high sensitivity. The research paper investigates the electrochemical sensing capabilities of a nanocomposite for detecting paracetamol. The nanocomposite is composed of reduced graphene oxide (rGO) decorated with zinc and copper-doped manganese ferrite (Mn 1−x Zn x Fe 2−y Cu y O 4 ). The primary goal is to develop an efficient and sensitive electrochemical sensor for the detection of paracetamol, a widely used analgesic, by utilizing the unique properties of the synthesized nanocomposite. rGO Provides a conductive and high-surface-area platform for the immobilization of the nanocomposite. Enhances electron transfer kinetics, crucial for sensitive electrochemical sensing. Tailored composition (Mn, Zn, Fe, Cu ratios) for optimized electrochemical performance. Nanocomposite’s unique properties enhance the selectivity and sensitivity of the sensor. Thorough characterization using techniques such as SEM, FT-IR, XRD, and Zeta Sizer, VSM to confirm nanocomposite structure and morphology. Utilization of CV, and EIS for paracetamol detection. Enhanced sensitivity and selectivity for paracetamol detection. The sensor demonstrates a wide linear r