Synthesis and Characterization of a New Cu (BHB) 2 /Fe-MIL-101-NH 2 Composite: A Novel Hydrogen Peroxide Sensor based upon the Bimetallic Complex

Hydrogen peroxide (H 2 O 2 ) serves a significant role in biological tissues. Throughout this manuscript, the synthesis of a copper complex on the Fe-MIL-101-NH 2 surface functionalized with 5-bromo-2-hydroxy-benzaldehyde (BHB), Cu(BHB) 2 /Fe-MIL-101-NH 2 composite was characterized by various techniques. The glassy carbon electrode (GCE) was modified with the Cu (BHB) 2 /Fe-MIL-101-NH 2 heterostructure to prepare Cu (BHB) 2 /Fe-MIL-101-NH 2 /GCE and used for the electrochemical detection of H 2 O 2 . The results showed that it had a good synergetic effect on the reduction of H 2 O 2 in a phosphate buffer solution (PBS) at the pH level of 7.4, in comparison with the bare GCE. The electrochemical methods were also performed for the characterization of the Cu (BHB) 2 /Fe-MIL-101-NH 2 , these included cyclic voltammetry (CV) and Chronoamperometry (CA). A quantitative H 2 O 2 detection was found with a wide linear response toward H 2 O 2 concentrations ranging from 0.05 to 3750 μ mol l −1 , with the limit of detection (LOD) being as low as 10 nmol l −1 . Finally, the Cu (BHB) 2 /Fe-MIL-101-NH 2 /GCE electrochemical sensor was effectively applied to H 2 O 2 detection, its applicability was investigated in various milk samples, displaying satisfactory results.