Au Nanoparticle-based Detection of Human Chorionic Gonadotropin Using Electrochemical Impedance Spectroscopy

Au Nanoparticle-based Detection of Human Chorionic Gonadotropin Using Electrochemical Impedance Spectroscopy

A disposable screen-printed carbon electrode (SPCE) for point-of-care detection platform was developed for human chorionic gonadotropin (hCG). A sandwich assay employing gold-nanoparticles was characterized with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). h...

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Hauptverfasser: Li, Nan, Li, Qi, Chen, Xavier Ran, Veloso, Anthony J., Hung, Vinci Wing Sze, Dhar, Devjani, Kerman, Kagan
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container_issue 28
container_start_page 15
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creator Li, Nan
Li, Qi
Chen, Xavier Ran
Veloso, Anthony J.
Hung, Vinci Wing Sze
Dhar, Devjani
Kerman, Kagan
description A disposable screen-printed carbon electrode (SPCE) for point-of-care detection platform was developed for human chorionic gonadotropin (hCG). A sandwich assay employing gold-nanoparticles was characterized with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). hCG was analyzed between 100 pg/mL and 1 ng/mL, and a detection limit of 100 pg/mL was observed with 2-µL sample volume. This versatile platform can be easily adapted for decentralized electrochemical immunosensing of clinically important hormones.
doi_str_mv 10.1149/05028.0015ecst
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identifier ISSN: 1938-5862
ispartof ECS transactions, 2013, Vol.50 (28), p.15-21
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1938-6737
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title Au Nanoparticle-based Detection of Human Chorionic Gonadotropin Using Electrochemical Impedance Spectroscopy
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