Multimodal probe for optical coherence tomography epidetection and micron-scale indentation

We present a multimodal ferrule-top sensor designed to perform the integrated epidetection of Optical Coherence Tomography (OCT) depth-profiles and micron-scale indentation by all-optical detection. By scanning a sample under the probe, we can obtain structural cross-section images and identify a region-of-interest in a nonhomogeneous sample. Then, with the same probe and setup, we can immediately target that area with a series of spherical-indentation measurements, in which the applied load is known with a μ N precision, the indentation depth with sub- μ m precision and a maximum contact radius of 100 μ m. Thanks to the visualization of the internal structure of the sample, we can gain a better insight into the observed mechanical behavior. The ability to impart a small, confined load, and perform OCT A -scans at the same time, could lead to an alternative, high transverse resolution, Optical Coherence Elastography (OCE) sensor.