SOME BASIC DERIVATIVES OF 6-CHLOROQUINAZOLINE AND PHTHALAZINE

SOME BASIC DERIVATIVES OF 6-CHLOROQUINAZOLINE AND PHTHALAZINE

Basic derivatives of 6-chloroquinazoline and phthalazine have been synthesized and screened for their physiological action on the central nervous system. Sodium dialkylaminoalkoxides and the appropriate chlorobenzodiazine were brought together to yield basic ethers of 6-chloroquinazoline and phthala...

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Veröffentlicht in:Canadian journal of chemistry 1956-11, Vol.34 (11), p.1557-1561
Hauptverfasser: Winthrop, Stanley O, Sybulski, Stella, Gaudry, Roger, Grant, Gordon A
Format: Artikel
Sprache:eng
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Zusammenfassung:Basic derivatives of 6-chloroquinazoline and phthalazine have been synthesized and screened for their physiological action on the central nervous system. Sodium dialkylaminoalkoxides and the appropriate chlorobenzodiazine were brought together to yield basic ethers of 6-chloroquinazoline and phthalazine respectively. 1-(γ-Dimethylaminopropylamino)phthalazine was also prepared.
ISSN:0008-4042
1480-3291
DOI:10.1139/v56-203