X-RAY NANOPHOSPHORS BASED ON BaGdF5 FOR X-RAY PHOTODYNAMIC THERAPY IN ONCOLOGY
X-ray and gamma radiation can be used to expand the possibilities of photodynamic therapy in the treatment of deep-lying tumors. One of the promising materials for converting X-ray radiation to optical radiation is BaGdF 5 nanoparticles doped with ions of rare-earth elements. It is shown that solvot...
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Veröffentlicht in: | Nanotechnologies in Russia 2020, Vol.15 (1), p.105-111 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | X-ray and gamma radiation can be used to expand the possibilities of photodynamic therapy in the treatment of deep-lying tumors. One of the promising materials for converting X-ray radiation to optical radiation is BaGdF
5
nanoparticles doped with ions of rare-earth elements. It is shown that solvothermal synthesis and a technique using microwave radiation lead to the production of BaGdF
5
:Eu nanoparticles with similar characteristics; however, when using microwave radiation, the time of the synthesis decreases by at least an order of magnitude. Microwave-synthesized doped BaGdF
5
:Eu nanoparticles are biocompatible and in terms of size (6–14 nm) meet the requirements for the subsequent preparation of nanocomposites based on them with the optical photosensitizers necessary for X-ray photodynamic therapy. |
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ISSN: | 1995-0780 1995-0799 |
DOI: | 10.1134/S1995078020010164 |