Reconstruction of connective tissue from fibrin-based dermal equivalent transplanted to animals with experimental wounds
Wound healing in rats transplanted with dermal equivalent (DE) based on fibrin with dermal fibroblasts has been examined in this work. Histological studies of biopsy samples from dermis newly formed in the process of the model wound recovery in laboratory animals have shown the positive influence of...
Gespeichert in:
Veröffentlicht in: | Cell and tissue biology 2010-10, Vol.4 (5), p.476-480 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Wound healing in rats transplanted with dermal equivalent (DE) based on fibrin with dermal fibroblasts has been examined in this work. Histological studies of biopsy samples from dermis newly formed in the process of the model wound recovery in laboratory animals have shown the positive influence of DE on wound healing. It was found that the area of collagen fibers, number of precapillaries, capillaries and post-capillaries in granulation tissue were significantly increased in animals with transplanted fibrin-based DE compared to the rats of the control group indicating more intensive repair. |
---|---|
ISSN: | 1990-519X 1990-5203 |
DOI: | 10.1134/S1990519X10050111 |