Modern conception on metabolism of γ-aminobutyric acid in the brain

Modern conception on metabolism of γ-aminobutyric acid in the brain

In this article, we review the recent data on GABA function in the central nervous system. We discuss the important role of the compartmental distribution of GABA metabolizing enzymes and the glutamate/GABA-glutamine cycle in the regulation of energy state and neuronal activity.

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Veröffentlicht in:Neurochemical journal 2009-12, Vol.3 (4), p.246-252
Hauptverfasser: Lelevich, V. V., Vinitskaya, A. G., Lelevich, S. V.
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Biomedicine
Neurosciences
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Zusammenfassung:In this article, we review the recent data on GABA function in the central nervous system. We discuss the important role of the compartmental distribution of GABA metabolizing enzymes and the glutamate/GABA-glutamine cycle in the regulation of energy state and neuronal activity.
ISSN:1819-7124
1819-7132
DOI:10.1134/S1819712409040023