Some regularities of the synthesis of ethyl 3-aryl-1,2,4-oxadiazole-5-carboxylates

Some regularities of the synthesis of ethyl 3-aryl-1,2,4-oxadiazole-5-carboxylates

Features of amidoximes reactions with ethyl chlorooxalate in a wide range of solvents at the use of a number of bases were investigated. An efficient preparation method for ethyl 3-aryl-1,2,4-oxadiazole-5-carboxylates in acetonitrile in the presence of triethylamine was developed.

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Veröffentlicht in:Russian journal of organic chemistry 2014-11, Vol.50 (11), p.1683-1686
Hauptverfasser: Voronova, A. A., Baikov, S. V., Krasovskaya, G. G., Kolobov, A. V., Kofanov, E. R.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Organic Chemistry
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Zusammenfassung:Features of amidoximes reactions with ethyl chlorooxalate in a wide range of solvents at the use of a number of bases were investigated. An efficient preparation method for ethyl 3-aryl-1,2,4-oxadiazole-5-carboxylates in acetonitrile in the presence of triethylamine was developed.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428014110232