Synthesis of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acids, intermediate products in the synthesis of cis-4-Aminochroman-3-ols

Synthesis of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acids, intermediate products in the synthesis of cis-4-Aminochroman-3-ols

Oxidation of accessible ( R )-3-chloropropane-1,2-diol to ( R )-3-chloro-2-hydroxypropanoic acid and subsequent reaction of the latter with ortho -substituted sodium phenoxide gave a number of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acid which are intermediate products in the synthesis of...

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Veröffentlicht in:Russian journal of organic chemistry 2014-04, Vol.50 (4), p.535-539
Hauptverfasser: Bredikhina, Z. A., Pashagin, A. V., Kurenkov, A. V., Bredikhin, A. A.
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Chemistry and Materials Science
Organic Chemistry
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Zusammenfassung:Oxidation of accessible ( R )-3-chloropropane-1,2-diol to ( R )-3-chloro-2-hydroxypropanoic acid and subsequent reaction of the latter with ortho -substituted sodium phenoxide gave a number of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acid which are intermediate products in the synthesis of nonracemic 4-aminochroman-3-ols.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428014040150