Azacycloalkanes from epoxides and aziridines

Methods of preparation of azetidines, pyrrolidines, and piperidines from epoxides and aziridines were analyzed. The possibility of epoxides conversion into aziridines was considered. The examples of application of azacycloalkanes in the medical and organic chemistry as biologically active substances...

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Veröffentlicht in:Russian journal of organic chemistry 2011-11, Vol.47 (11), p.1609-1652
Hauptverfasser: Kas’yan, L. I., Pal’chikov, V. A., Bondarenko, Ya. S.
Format: Artikel
Sprache:eng
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Zusammenfassung:Methods of preparation of azetidines, pyrrolidines, and piperidines from epoxides and aziridines were analyzed. The possibility of epoxides conversion into aziridines was considered. The examples of application of azacycloalkanes in the medical and organic chemistry as biologically active substances and synthons for their preparation were calculated.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428011110017