Halocyclization of 2-(2-{4-[allylamino(thioxo)methyl]piperazin-1-yl}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
Cyclization of 2-(2-{4-[allylamino(thioxo)methyl]piperazin-1-yl}ethyl)-1 H -benzo[ de ]isoquinoline-1,3(2 H )-dione by the action of iodine, bromine, or sulfuryl chloride gave 2-(2-{4-[4,5-dihydro-5-(halomethyl)-thiazol-2-yl]piperazin-1-yl}ethyl)-1 H -benzo[ de ]isoquinoline-1,3(2 H )-dione hydrohal...
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| Veröffentlicht in: | Russian journal of organic chemistry 2011-06, Vol.47 (6), p.881-885 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Cyclization of 2-(2-{4-[allylamino(thioxo)methyl]piperazin-1-yl}ethyl)-1
H
-benzo[
de
]isoquinoline-1,3(2
H
)-dione by the action of iodine, bromine, or sulfuryl chloride gave 2-(2-{4-[4,5-dihydro-5-(halomethyl)-thiazol-2-yl]piperazin-1-yl}ethyl)-1
H
-benzo[
de
]isoquinoline-1,3(2
H
)-dione hydrohalides which were converted into 2-{2-[4-(5-methylthiazol-2-yl)piperazin-1-yl]ethyl}-1
H
-benzo[
de
]isoquinoline-1,3(2
H
)-dione. |
|---|---|
| ISSN: | 1070-4280 1608-3393 |
| DOI: | 10.1134/S107042801106008X |