Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety

3-Aryl-5-[( Z )-pyrenylmethylene]-2-alkylthiohydantoins and 3-Aryl-5-[( Z )-pyrenylmethylene]-2-( D -glycosyl)-2-thiohydantoins functionalized with different aromatic and glycoside substituents have been synthesized by the reaction of ( Z )-3-(4-methoxyphenyl)-5-[(pyren-8-yl)methylene]-2-thiohydantoin with alkyl halides, cyclic and acyclic nucleosides via various routes with moderate to good yields and characterized by 1 H, 13 C NMR and mass spectra and elemental analysis