Asymmetric hydrogenation of 3-chloro-1-phenylpropan-1-one catalyzed by ruthenium complexes

A ruthenium complex modified with (1 S ,2 S )-1,2-diphenyl-1,2-ethanediamine efficiently catalyzes asymmetric hydrogenation of 3-chloro-1-phenylpropan-1-one in the presence of potassium hydroxide solution in isopropyl alcohol, specific optical rotation of the synthesized products reaching −24.6°. Ef...

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Veröffentlicht in:	Russian journal of general chemistry 2015-04, Vol.85 (4), p.922-925
Hauptverfasser:	Liu, Yanmei, Tai, Yulei, Guan, Ruqi, Chao, Guoku, Ye, Caiping, Li, Haihua, Li, Xiaoyan, Zhao, Yajuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry and Materials Science Chemistry/Food Science
Online-Zugang:	Volltext
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Zusammenfassung:	A ruthenium complex modified with (1 S ,2 S )-1,2-diphenyl-1,2-ethanediamine efficiently catalyzes asymmetric hydrogenation of 3-chloro-1-phenylpropan-1-one in the presence of potassium hydroxide solution in isopropyl alcohol, specific optical rotation of the synthesized products reaching −24.6°. Effects of the reaction time, hydrogen pressure, and the alkali concentration on the reaction course have been elucidated.
ISSN:	1070-3632 1608-3350
DOI:	10.1134/S1070363215040271