Experimental study and simulation of kinetics of acetophenone hydrosilylation with diphenylsilane in the presence of rhodium complexes in a microreactor

The hydrosilylation of acetophenone with diphenylsilane in a microreactor in the presence of complexes [Rh(cod)Cl] 2 and [Rh(CO) 2 (μ-Cl)] 2 and ( R )-(-)- cis -mirtanyl- and ( R )-(+)-bornylamine in situ was studied, the kinetics simulation of the process was performed, and the multicriteria optimization of the process was carried out. The influence of the micro-mixing effect on the reaction rate was revealed. Best results in the microreactor were obtained for the [Rh(cod)Cl] 2 -BornylNH2 catalytic system. It was established that the formation of 1-phenylethanol and related enol silyl ethers are simultaneous competing reactions.