Conjugates of cyclooligosaccharide scaffolds and carbohydrate ligands: Methods for synthesis and the interaction with lectins

Conjugates of cyclooligosaccharide scaffolds and carbohydrate ligands: Methods for synthesis and the interaction with lectins

The main approaches to the preparation of mono- and oligodentate glycoconjugates based on cyclodextrin and cyclooligo-β-(1 → 6)-D-glucosamine scaffolds are surveyed in the review. The data on the biological activity of the glycoconjugates are discussed exemplified in their interaction with carbohydr...

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Veröffentlicht in:Russian journal of bioorganic chemistry 2013-09, Vol.39 (5), p.451-487
Hauptverfasser: Titov, D. V., Gening, M. L., Tsvetkov, Yu. E., Nifantiev, N. E.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Bioorganic Chemistry
Life Sciences
Organic Chemistry
Review Article
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Zusammenfassung:The main approaches to the preparation of mono- and oligodentate glycoconjugates based on cyclodextrin and cyclooligo-β-(1 → 6)-D-glucosamine scaffolds are surveyed in the review. The data on the biological activity of the glycoconjugates are discussed exemplified in their interaction with carbohydrate-binding proteins named lectins.
ISSN:1068-1620
1608-330X
DOI:10.1134/S1068162013050142