Myelopeptide MP-5 and fluorescent derivatives: Synthesis and biological activity

The Val-Val-Tyr-Pro-Asp bone marrow peptide (MP-5) and its analogue (MP-5-Lys) were synthesized. Fluorescent derivatives, Ftc-MP-5 and MP-5-Lys(Ftc), were prepared. The iological activity of MP-5 and MP-5-Lys was studied in vitro and in vivo. The MP-5 peptide caused 60–84% inhibition of growth of th...

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Veröffentlicht in:	Russian journal of bioorganic chemistry 2008-07, Vol.34 (4), p.404-408
Hauptverfasser:	Fonina, L. A., Az’muko, A. A., Kalikhevich, V. N., Lewit, M. L., Ardemasova, Z. A., Gur’yanov, S. A., Belevskaya, R. G., Efremov, M. A., Treshchalina, E. M., Mikhailova, A. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Life Sciences Organic Chemistry Review Articles
Online-Zugang:	Volltext
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