Adsorption equilibriums in a silica-poly(vinyl alcohol)-gelatin system

The interaction of gelatin with nonporous nanosized amorphous silica containing poly(vinyl alcohol) (PVA) preliminarily adsorbed on its surface is studied. It is established that the modification of the nanosilica via PVA adsorption does not influence its ability to adsorb the protein. It is shown that, during adsorption, gelatin partly displaces PVA molecules from the silica surface. It is assumed that hydroxyl groups of strongly retained PVA macromolecules may play the role of active sites of protein adsorption along with free silanol groups.