Analysis of peanut gene RNAi in drosophila oogenesis

The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in follicle cells led to oocyte polarization defects, anomalous cytokinesis in the chorion cells, and aberrant chromatin condensation in foll...

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Veröffentlicht in:	Russian journal of genetics 2015-09, Vol.51 (9), p.847-854
Hauptverfasser:	Akhmetova, K. A, Dorogova, N. V, Chesnokov, I. N, Fedorova, S. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Biomedical and Life Sciences Biomedicine chorion chromatin cytokinesis Drosophila melanogaster embryonic mortality females gene expression General Genetics genes Human Genetics Microbial Genetics and Genomics oocytes oogenesis peanuts RNA interference survival rate
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Zusammenfassung:	The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in follicle cells led to oocyte polarization defects, anomalous cytokinesis in the chorion cells, and aberrant chromatin condensation in follicle cells. No oogenesis abnormalities were observed in females with decreased peanut gene expression in ovarian germline cells. However, embryos produced by such females had a decreased survival rate caused by two peaks of embryonic death.
ISSN:	1022-7954 1608-3369
DOI:	10.1134/S1022795415090021