Synthesis and antioxidant activity of biocompatible maltodextrin-stabilized aqueous sols of nanocrystalline ceria

A novel method is proposed for preparing biocompatible aqueous CeO 2 sols, which allows purposefully adjusting particle sizes and biochemical properties of nanocrystalline ceria (NC). The usefulness of this method for preparing aqueous sols of Ce 1 − x Gd x O 2 − x /2 solid solutions is demonstrated...

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Veröffentlicht in:Russian journal of inorganic chemistry 2012-11, Vol.57 (11), p.1411-1418
Hauptverfasser: Shcherbakov, A. B., Zholobak, N. M., Ivanov, V. K., Ivanova, O. S., Marchevsky, A. V., Baranchikov, A. E., Spivak, N. Ya, Tretyakov, Yu. D.
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Sprache:eng
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Zusammenfassung:A novel method is proposed for preparing biocompatible aqueous CeO 2 sols, which allows purposefully adjusting particle sizes and biochemical properties of nanocrystalline ceria (NC). The usefulness of this method for preparing aqueous sols of Ce 1 − x Gd x O 2 − x /2 solid solutions is demonstrated. Nanocrystalline ceria has been demonstrated to have a size-dependent activity in hydroxyl radical inactivation and in protecting mouse fibroblast cells (L929) from oxidative stress induced by hydrogen peroxide administration.
ISSN:0036-0236
1531-8613
DOI:10.1134/S0036023612110137